C10orf2 Antibody

Primary Antibodies

Blue Ice

77 kDa

This gene encodes a hexameric DNA helicase which unwinds
short stretches of double-stranded DNA in the 5' to 3' direction
and, along with mitochondrial single-stranded DNA binding protein
and mtDNA polymerase gamma, is thought to play a key role in mtDNA
replication. The protein localizes to the mitochondrial matrix and
mitochondrial nucleoids. Mutations in this gene cause infantile
onset spinocerebellar ataxia (IOSCA) and progressive external
ophthalmoplegia (PEO) and are also associated with several
mitochondrial depletion syndromes. Alternative splicing results in
multiple transcript variants encoding distinct isoforms.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This C10orf2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-684 amino acids from the C-terminal region of human C10orf2.

Twinkle protein, mitochondrial

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.