SPAG8 Antibody

Primary Antibodies

Blue Ice

45 kDa

The correlation of anti-sperm antibodies with cases of
unexplained infertility implicates a role for these antibodies in
blocking fertilization. Improved diagnosis and treatment of
immunologic infertility, as well as identification of proteins for
targeted contraception, are dependent on the identification and
characterization of relevant sperm antigens. The protein encoded by
this gene is recognized by sperm agglutinating antibodies from an
infertile woman. This protein is localized in germ cells of the
testis at all stages of spermatogenesis and is localized to the
acrosomal region of mature spermatozoa. Alternatively spliced
variants that encode different protein isoforms have been described
but the full-length sequences of only two have been determined.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This SPAG8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 383-411 amino acids from the C-terminal region of human SPAG8.

Sperm-associated antigen 8

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.