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Bcl-w Antibody

ArtNr PRS-56-826-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Denisov, A.Y., et al., J. Biol. Chem. 278(23):21124-21128 (2003).
Hinds, M.G., et al., EMBO J. 22(7):1497-1507 (2003).
Middleton, G., et al., Development 128(3):447-457 (2001).
Ross, A.J., et al., Nat. Genet. 18(3):251-256 (1998).
NCBI BCL2L2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Bcl-2-like protein 2,Bcl2-L-2,Apoptosis regulator Bcl-W,BCL2L2,BCLW,KIAA0271
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
21 kDa
Manufacturer - Research Area
Cancer, Cell Cycle
Background
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
By Type
Cancer, Cell Cycle
Modifications
None
Protein Gi #
296434404
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen
This Bcl antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-59 amino acids from human Bcl.
Clonality
Polyclonal
NCBI Official Name
Bcl-2-like protein 2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
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