CD1C Antibody

Primary Antibodies

Blue Ice

38 kDa

This gene encodes a member of the CD1 family of
transmembrane glycoproteins, which are structurally related to the
major histocompatibility complex (MHC) proteins and form
heterodimers with beta-2-microglobulin. The CD1 proteins mediate
the presentation of primarily lipid and glycolipid antigens of self
or microbial origin to T cells. The human genome contains five CD1
family genes organized in a cluster on chromosome 1. The CD1 family
members are thought to differ in their cellular localization and
specificity for particular lipid ligands. The protein encoded by
this gene is broadly distributed throughout the endocytic system
via a tyrosine-based motif in the cytoplasmic tail. Alternatively
spliced transcript variants of this gene have been observed, but
their full-length nature is not known.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This CD1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-253 amino acids from the C-terminal region of human CD1C.

T-cell surface glycoprotein CD1c

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.