SF3B1 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene encodes subunit 1 of the splicing factor 3b
protein complex. Splicing factor 3b, together with splicing factor
3a and a 12S RNA unit, forms the U2 small nuclear
ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a
complex binds pre-mRNA upstream of the intron's branch site in a
sequence independent manner and may anchor the U2 snRNP to the
pre-mRNA. Splicing factor 3b is also a component of the minor
U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1
have 22 non-identical, tandem HEAT repeats that form rod-like,
helical structures. Alternative splicing results in multiple
transcript variants encoding different isoforms. [provided by
RefSeq].

None

batch dependent

For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50

This SF3B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the N-terminal region of human SF3B1.

Splicing factor 3B subunit 1

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.