RLN1/RLN2 Antibody

Primary Antibodies

Blue Ice

21 kDa

Relaxins are known endocrine and autocrine/paracrine
hormones, belonging to the insulin gene superfamily. In the human
there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.
RLN1 and RLN2 share high sequence homology. This encoded protein is
synthesized as a single-chain polypeptide but the active form
consists of an A chain and a B chain linked by disulfide bonds;
however, their exact cleavage sites have not been described.
Relaxin is produced by the ovary, and targets the mammalian
reproductive system to ripen the cervix, elongate the pubic
symphysis and inhibit uterine contraction. It may have additional
roles in enhancing sperm motility, regulating blood pressure,
controlling heart rate and releasing oxytocin and vasopressin. This
gene has multiple polyadenylation sites. There are multiple
alternatively spliced transcript variants described for this gene
but their full length nature is not known yet. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This RLN1/RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-165 amino acids from the C-terminal region of human RLN1/RLN2.

Prorelaxin H1

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.