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Mouse Abl1 Antibody

ArtNr PRS-57-346-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IHC-P
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Ko, H.S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(38):16691-16696(2010)
Yamaguchi, T., et al. Apoptosis 15(8):927-935(2010)
Michael, M., et al. Curr. Biol. 20(9):783-791(2010)
Swimm, A.I., et al. J. Virol. 84(9):4243-4251(2010)
NCBI Abl1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tyrosine-protein kinase ABL1,Abelson murine leukemia viral oncogene homolog 1,Abelson tyrosine-protein kinase 1,Proto-oncogene c-Abl,p150,Abl1,Abl
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
123 kDa
Manufacturer - Research Area
Cancer, Signal Transduction
Background
Protein kinase that regulates key processes linked to cell growth and survival. Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.
By Type
Cancer, Signal Transduction
Modifications
None
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Immunogen
This Mouse Abl1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 613-641 amino acids from the Central region of mouse Abl1.
Clonality
Polyclonal
NCBI Official Name
Tyrosine-protein kinase ABL1
NCBI Organism
Mus musculus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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