HNRNPM Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene belongs to the subfamily of ubiquitously
expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The
hnRNPs are RNA binding proteins and they complex with heterogeneous
nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs
in the nucleus and appear to influence pre-mRNA processing and
other aspects of mRNA metabolism and transport. While all of the
hnRNPs are present in the nucleus, some seem to shuttle between the
nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic
acid binding properties. The protein encoded by this gene has three
repeats of quasi-RRM domains that bind to RNAs. This protein also
constitutes a monomer of the N-acetylglucosamine-specific receptor
which is postulated to trigger selective recycling of immature
GlcNAc-bearing thyroglobulin molecules. Multiple alternatively
spliced transcript variants are known for this gene but only two
transcripts has been isolated.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This HNRNPM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human HNRNPM.

Heterogeneous nuclear ribonucleoprotein M

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.