MCM3 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

The protein encoded by this gene is one of the highly
conserved mini-chromosome maintenance proteins (MCM) that are
involved in the initiation of eukaryotic genome replication. The
hexameric protein complex formed by MCM proteins is a key component
of the pre-replication complex (pre_RC) and may be involved in the
formation of replication forks and in the recruitment of other DNA
replication related proteins. This protein is a subunit of the
protein complex that consists of MCM2-7. It has been shown to
interact directly with MCM5/CDC46. This protein also interacts
with, and thus is acetlyated by MCM3AP, a chromatin-associated
acetyltransferase. The acetylation of this protein inhibits the
initiation of DNA replication and cell cycle progression. [provided
by RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine, Mouse

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.