UBA7 Antibody

Primary Antibodies

Blue Ice

112 kDa

The modification of proteins with ubiquitin is an
important cellular mechanism for targeting abnormal or short-lived
proteins for degradation. Ubiquitination involves at least three
classes of enzymes: ubiquitin-activating enzymes, or E1s,
ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein
ligases, or E3s. This gene encodes a member of the E1
ubiquitin-activating enzyme family. The encoded enzyme is a
retinoid target that triggers promyelocytic leukemia (PML)/retinoic
acid receptor alpha (RARalpha) degradation and apoptosis in acute
promyelocytic leukemia, where it is involved in the conjugation of
the ubiquitin-like interferon-stimulated gene 15 protein. [provided
by RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This UBA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the N-terminal region of human UBA7.

Ubiquitin-like modifier-activating enzyme 7

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.