RNF19A Antibody

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

blue ice or room temperature

91 kDa

The protein encoded this gene contains two RING-fingermotifs and an IBR (in between RING fingers) motif. This protein isan E3 ubiquintin ligase that is localized in Lewy bodies (LBs), acharacteristic neuronal inclusion in Parkinson's disease (PD)brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is foundto bind and ubiquitylate synphilin 1 (SNCAIP), which is ainteracting protein of alpha synuclein in neurons, and a majorcomponent of LB. Alternatively spliced transcript variants encodingthe same protein have been reported.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A.

E3 ubiquitin-protein ligase RNF19A

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.