RNF19A Antibody

ArtNr	PRS-57-576-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Food Safety Allergenes Neuroscience Neural Signaling Antibodies Immunohistochemistry Western Blot Primary Antibodies By Organ Bladder Cancer Heart & Blood Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Huh, J.W., et al. Gene 424 (1-2), 63-70 (2008) : Matsuoka, S., et al. Science 316(5828):1160-1166(2007) Ishigaki, S., et al. Neurobiol. Dis. 25(2):331-341(2007) Huang, Y., et al. J. Biol. Chem. 281(17):11610-11617(2006)
NCBI	RNF19A
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 ubiquitin-protein ligase RNF19A,632-,Double ring-finger protein,Dorfin,RING finger protein 19A,p38,RNF19A,RNF19
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	91 kDa
Manufacturer - Research Area	Cell Cycle, Neuroscience
Background	The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
By Type	Cell Cycle, Neuroscience
Modifications	None
Protein Gi #	116242764
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Pig
Immunogen	This RNF19A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-413 amino acids from the Central region of human RNF19A.
Clonality	Polyclonal
NCBI Official Name	E3 ubiquitin-protein ligase RNF19A
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.11.2025

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