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TPX2 Antibody

ArtNr PRS-57-812-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Bibby, R.A., et al. J. Biol. Chem. 284(48):33177-33184(2009)
Shigeishi, H., et al. Int. J. Oncol. 34(6):1565-1571(2009)
NCBI TPX2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Targeting protein for Xklp2, Differentially expressed in cancerous and non-cancerous lung cells 2, DIL-2, Hepatocellular carcinoma-associated antigen 519, Hepatocellular carcinoma-associated antigen 90, Protein fls353, Restricted expression proliferation-
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
86 kDa
Manufacturer - Research Area
Cancer, Cell Cycle
Background
TPX2 is a spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
By Type
Cancer, Cell Cycle
Modifications
None
Protein Gi #
13124096
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen
This TPX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-448 amino acids from the Central region of human TPX2.
Clonality
Polyclonal
NCBI Official Name
Targeting protein for Xklp2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names
Targeting protein for Xklp2, Differentially expressed in cancerous and non-cancerous lung cells 2, DIL-2, Hepatocellular carcinoma-associated antigen 519, Hepatocellular carcinoma-associated antigen 90, Protein fls353, Restricted expression proliferation-associated protein 100, p100, TPX2, C20orf1, C20orf2, DIL2, HCA519

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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