ADRA2C Antibody

Primary Antibodies

Blue Ice

50 kDa

Alpha-2-adrenergic receptors are members of the G
protein-coupled receptor superfamily. They include 3 highly
homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors
have a critical role in regulating neurotransmitter release from
sympathetic nerves and from adrenergic neurons in the central
nervous system. The mouse studies revealed that both the alpha2A
and alpha2C subtypes were required for normal presynaptic control
of transmitter release from sympathetic nerves in the heart and
from central noradrenergic neurons. The alpha2A subtype inhibited
transmitter release at high stimulation frequencies, whereas the
alpha2C subtype modulated neurotransmission at lower levels of
nerve activity. This gene encodes the alpha2C subtype, which
contains no introns in either its coding or untranslated sequences.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.