SNAP23 Antibody

Primary Antibodies

Blue Ice

23 kDa

Specificity of vesicular transport is regulated, in part,
by the interaction of a vesicle-associated membrane protein termed
synaptobrevin/VAMP with a target compartment membrane protein
termed syntaxin. These proteins, together with SNAP25
(synaptosome-associated protein of 25 kDa), form a complex which
serves as a binding site for the general membrane fusion machinery.
Synaptobrevin/VAMP and syntaxin are believed to be involved in
vesicular transport in most, if not all cells, while SNAP25 is
present almost exclusively in the brain, suggesting that a
ubiquitously expressed homolog of SNAP25 exists to facilitate
transport vesicle/target membrane fusion in other tissues. The
protein encoded by this gene is structurally and functionally
similar to SNAP25 and binds tightly to multiple syntaxins and
synaptobrevins/VAMPs. It is an essential component of the high
affinity receptor for the general membrane fusion machinery and is
an important regulator of transport vesicle docking and fusion. Two
alternative transcript variants encoding different protein isoforms
have been described for this gene.

None

batch dependent

For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.