PSMD1 Antibody

ArtNr	PRS-57-850-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies Western Blot Cardiovascular Research Heart Failure Hypertension Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Bailey, S.D., et al. Diabetes Care (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) da Fonseca, P.C., et al. J. Biol. Chem. 283(34):23305-23314(2008)
NCBI	PSMD1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	26S proteasome non-ATPase regulatory subunit 1,26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112,PSMD1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	106 kDa
Manufacturer - Research Area	Cell Cycle, Signal Transduction
Background	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq].
By Type	Cell Cycle, Signal Transduction
Modifications	None
Protein Gi #	51704332
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen	This PSMD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-132 amino acids from the N-terminal region of human PSMD1.
Clonality	Polyclonal
NCBI Official Name	26S proteasome non-ATPase regulatory subunit 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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