LRP5 Antibody

Primary Antibodies

Blue Ice

179 kDa

This gene encodes a transmembrane low-density lipoprotein
receptor that binds and internalizes ligands in the process of
receptor-mediated endocytosis. This protein also acts as a
co-receptor with Frizzled protein family members for transducing
signals by Wnt proteins and was originally cloned on the basis of
its association with type 1 diabetes mellitus in humans. This
protein plays a key role in skeletal homeostasis and many bone
density related diseases are caused by mutations in this gene.
Mutations in this gene also cause familial exudative
vitreoretinopathy.

None

batch dependent

For WB starting dilution is: 1:1000

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.