CPT1A Antibody

Primary Antibodies

Blue Ice

88 kDa

The mitochondrial oxidation of long-chain fatty acids is
initiated by the sequential action of carnitine
palmitoyltransferase I (which is located in the outer membrane and
is detergent-labile) and carnitine palmitoyltransferase II (which
is located in the inner membrane and is detergent-stable), together
with a carnitine-acylcarnitine translocase. CPT I is the key enzyme
in the carnitine-dependent transport across the mitochondrial inner
membrane and its deficiency results in a decreased rate of fatty
acid beta-oxidation. Alternatively spliced transcript variants
encoding different isoforms have been found for this gene.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This CPT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 728-756 amino acids from the C-terminal region of human CPT1A.

Carnitine O-palmitoyltransferase 1, liver isoform

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.