Mouse Akt1 Antibody

Primary Antibodies

Blue Ice

56 kDa

This gene encodes the founding member of the Akt
serine-threonine protein kinase gene family that also includes Akt2
and Akt3. This kinase is a major downstream effector of the
phosphatidylinositol 3-kinase (PI3K) pathway that mediates the
effects of various growth factors such as platelet-derived growth
factor (PDGF), epidermal growth factor (EGF), insulin and
insulin-like growth factor I (IGF-I). It is activated through
recruitment to cellular membranes by PI3K lipid products and by
phosphorylation by 3-phosphoinositide dependent kinase-1. It then
further phosphorylates different downstream proteins in response to
various extracellular signals and thus plays a pivotal role in
mediating a variety of cellular processes, such as glucose
metabolism, glycogen biosynthesis, protein synthesis and turn over,
inflammatory response, cell survival (anti-apoptosis) and
development. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].

None

batch dependent

For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50

This Mouse Akt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-49 amino acids from the N-terminal region of mouse Akt1.

RAC-alpha serine/threonine-protein kinase

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.