RBM5 Antibody

ArtNr	PRS-58-082-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Western Blot Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Sugliani, M., et al. Plant Cell 22(6):1936-1946(2010) Rintala-Maki, N.D., et al. Gene 445 (1-2), 7-16 (2009) : Kotlajich, M.V., et al. Mol. Cell 32(2):162-164(2008) Fushimi, K., et al. Proc. Natl. Acad. Sci. U.S.A. 105(41):15708-15713(2008)
NCBI	RBM5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	RNA-binding protein 5,Protein G15,Putative tumor suppressor LUCA15,RNA-binding motif protein 5,Renal carcinoma antigen NY-REN-9,RBM5
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	92 kDa
Manufacturer - Research Area	Cancer
Background	Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
By Type	Cancer
Modifications	None
Protein Gi #	13124794
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000
Homology	Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen	This RBM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human RBM5.
Clonality	Polyclonal
NCBI Official Name	RNA-binding protein 5
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 01.01.2026

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