DNMT3A Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

CpG methylation is an epigenetic modification that is
important for embryonic development, imprinting, and X-chromosome
inactivation. Studies in mice have demonstrated that DNA
methylation is required for mammalian development. This gene
encodes a DNA methyltransferase that is thought to function in de
novo methylation, rather than maintenance methylation. The protein
localizes to the cytoplasm and nucleus and its expression is
developmentally regulated. Alternative splicing results in multiple
transcript variants encoding different isoforms. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.