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ARHGEF11 Antibody

ArtNr PRS-58-813-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Akiyama, K., et al. J. Hum. Genet. (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ying, Z., et al. Arterioscler. Thromb. Vasc. Biol. 29(10):1657-1663(2009)
Banerjee, J., et al. Biochemistry 48(33):8032-8043(2009)
NCBI ARHGEF11
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Rho guanine nucleotide exchange factor 11,PDZ-RhoGEF,ARHGEF11,KIAA0380
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
168 kDa
Manufacturer - Research Area
Signal Transduction
Background
Rho GTPases play a fundamental role in numerous cellular
processes that are initiated by extracellular stimuli that work
through G protein coupled receptors. The encoded protein may form a
complex with G proteins and stimulate Rho-dependent signals. A
similar protein in rat interacts with glutamate transporter EAAT4
and modulates its glutamate transport activity. Expression of the
rat protein induces the reorganization of the actin cytoskeleton
and its overexpression induces the formation of membrane ruffling
and filopodia. Two alternative transcripts encoding different
isoforms have been described.
By Type
Signal Transduction
Modifications
None
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
Homology
Predicted species reactivity based on immunogen sequence: Rat
Immunogen
This ARHGEF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605-632 amino acids from the Central region of human ARHGEF11.
Clonality
Polyclonal
NCBI Official Name
Rho guanine nucleotide exchange factor 11
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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