RAPGEF5 Antibody

ArtNr	PRS-58-923-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010) Hwang, S.J., et al. BMC Med. Genet.SUPPL 1, S10 (2007) : Rebhun, J.F., et al. J. Biol. Chem. 275(45):34901-34908(2000)
NCBI	RAPGEF5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Rap guanine nucleotide exchange factor 5, Guanine nucleotide exchange factor for Rap1, M-Ras-regulated Rap GEF, MR-GEF, Related to Epac, Repac, RAPGEF5, GFR, KIAA0277, MRGEF
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Manufacturer - Applications	For WB starting dilution is: 1:1000
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	68 kDa
Manufacturer - Research Area	Neuroscience, Signal Transduction
Background	Members of the RAS (see HRAS; MIM 190020) subfamily ofGTPases function in signal transduction as GTP/GDP-regulatedswitches that cycle between inactive GDP- and active GTP-boundstates. Guanine nucleotide exchange factors (GEFs), such asRAPGEF5, serve as RAS activators by promoting acquisition of GTP tomaintain the active GTP-bound state and are the key link betweencell surface receptors and RAS activation (Rebhun et al., 2000[PubMed 10934204]).
Protein Gi #	32171396
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This RAPGEF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 529-555 amino acids from the C-terminal region of human RAPGEF5.
Clonality	Polyclonal
NCBI Official Name	Rap guanine nucleotide exchange factor 5
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 02.10.2025

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