CD68/CD68 Antibody

Primary Antibodies

Blue Ice

37 kDa

This gene encodes a 110-kD transmembrane glycoprotein that
is highly expressed by human monocytes and tissue macrophages. It
is a member of the lysosomal/endosomal-associated membrane
glycoprotein (LAMP) family. The protein primarily localizes to
lysosomes and endosomes with a smaller fraction circulating to the
cell surface. It is a type I integral membrane protein with a
heavily glycosylated extracellular domain and binds to tissue- and
organ-specific lectins or selectins. The protein is also a member
of the scavenger receptor family. Scavenger receptors typically
function to clear cellular debris, promote phagocytosis, and
mediate the recruitment and activation of macrophages. Alternative
splicing results in multiple transcripts encoding different
isoforms.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This CD68/CD68 (kpi) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-237 amino acids from the Central region of human CD68/CD68 (kpi).

Macrosialin

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.