PPFIBP1 Antibody

For WB starting dilution is: 1:2000

blue ice or room temperature

114 kDa

The protein encoded by this gene is a member of the LARprotein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembraneprotein tyrosine phosphatases, which are known to be important foraxon guidance and mammary gland development. It has been proposedthat liprins are multivalent proteins that form complex structuresand act as scaffolds for the recruitment and anchoring of LARfamily of tyrosine phosphatases. This protein was found to interactwith S100A4, a calcium-binding protein related to tumorinvasiveness and metastasis. In vitro experiment demonstrated thatthe interaction inhibited the phosphorylation of this protein byprotein kinase C and protein kinase CK2. Alternatively splicedtranscript variants encoding distinct isoforms have been reported.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1.

Liprin-beta-1

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.