TEF Antibody

Primary Antibodies

Blue Ice

33 kDa

Thyrotroph embryonic factor (TEF), a transcription factor,
is a member of the PAR (proline and acidic amino acid-rich)
subfamily of basic region/leucine zipper (bZIP) transcription
factors. It is expressed in a broad range of cells and tissues in
adult animals, however, during embryonic development, TEF
expression appears to be restricted to the developing anterior
pituitary gland, coincident with the appearance of
thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to,
and transactivate the TSHB promoter. It shows homology (in the
functional domains) with other members of the PAR-bZIP subfamily of
transcription factors, which include albumin D box-binding protein
(DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin
gene-binding protein (VBP); VBP is considered the chicken homologue
of TEF. Different members of the subfamily can readily form
heterodimers, and share DNA-binding, and transcriptional regulatory
properties. Alternatively spliced transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Chicken, Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.