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HERC3 Antibody

HERC3 Antibody

Hersteller	ProSci
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Specific against	Human
Format	Liquid
Applikationen	WB
Menge	400 ul
Host	Rabbit
ArtNr	PRS-60-595-400ul
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Shipping	blue ice or RT
By Research Area	Cell Cycle
Immunogen	This HERC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-77 amino acids from the N-terminal region of human HERC3.
Applications	For WB starting dilution is: 1:1000
Predicted Molecular Weight	117 kDa
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality	Polyclonal
Isotype	Rabbit Ig
Conjugate	Unconjugated
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration	batch dependent
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Modifications	None
Ncbi Official Symbol	HERC3
Accession #	Q15034
Protein Gi #	2495699
Ncbi Gene Id #	8916
User Note	Optimal dilutions for each application to be determined by the researcher.
Ncbi Official Symbol	HERC3
Ncbi Official Full Name	Probable E3 ubiquitin-protein ligase HERC3
Ncbi Organism	Homo sapiens
Swissprot #	Q15034
Background	HERC3 belongs to the HERC family of ubiquitin ligases, allof which contain a HECT domain and at least 1 RCC1 (MIM179710)-like domain (RLD). The 350-amino acid HECT domain ispredicted to catalyze the formation of a thioester with ubiquitinbefore transferring it to a substrate, and the RLD is predicted toact as a guanine nucleotide exchange factor for small G proteins(Hochrainer et al., 2005 [PubMed 15676274]).
Background References 1	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background References 2	Hochrainer, K., et al. Genomics 85(2):153-164(2005)
Background References 3	Cruz, C., et al. FEBS Lett. 488 (1-2), 74-80 (2001) :
Background References 4	Cruz, C., et al. Cytogenet. Cell Genet. 87 (3-4), 263-264 (1999) :
1st Image Caption	Western blot analysis in K562 cell line lysates (35ug/lane).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 06.06.2024

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