MTA1 Antibody

Rabbit Ig

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene encodes a protein that was identified in a
screen for genes expressed in metastatic cells, specifically,
mammary adenocarcinoma cell lines. Expression of this gene has been
correlated with the metastatic potential of at least two types of
carcinomas although it is also expressed in many normal tissues.
The role it plays in metastasis is unclear. It was initially
thought to be the 70kD component of a nucleosome remodeling
deacetylase complex, NuRD, but it is more likely that this
component is a different but very similar protein. These two
proteins are so closely related, though, that they share the same
types of domains. These domains include two DNA binding domains, a
dimerization domain, and a domain commonly found in proteins that
methylate DNA. The profile and activity of this gene product
suggest that it is involved in regulating transcription and that
this may be accomplished by chromatin remodeling. [provided by
RefSeq].

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Rat

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.