CREB3 Antibody

Rabbit Ig

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds to the cAMP-response element and regulates cellproliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) proteinVP16 that induces transcription of HSV immediate-early genes. Thisprotein and VP16 both bind to the same site on host cell factor C1.It is thought that the interaction between this protein and hostcell factor C1 plays a role in the establishment of latency duringHSV infection. This protein also plays a role in leukocytemigration, tumor suppression, and endoplasmic reticulumstress-associated protein degradation. Additional transcriptvariants have been identified, but their biological validity hasnot been determined.

Batch dependent

This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.

Cyclic AMP-responsive element-binding protein 3

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.