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BMPR1A Antibody

ArtNr PRS-60-842-200ul
Hersteller ProSci
Menge 200 ul
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Zhou, X.-P., et al., Am. J. Hum. Genet. 69(4):704-711 (2001).
Howe, J.R., et al., Nat. Genet. 28(2):184-187 (2001).
ten Dijke, P., et al., Oncogene 8(10):2879-2887 (1993).
NCBI BMPR1A
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD292, BMPR1A, ACVRLK3, ALK3
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
60 kDa
Manufacturer - Research Area
Obesity, Signal Transduction
Background
The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Protein Gi #
61252444
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This BMPR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-195 amino acids from the Central region of human BMPR1A.
Clonality
Polyclonal
NCBI Official Name
Bone morphogenetic protein receptor type-1A
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ul
Lieferbar: In stock
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