MTHFD1 Antibody

ArtNr	PRS-61-504-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Skin Cancer Adhesion Molecule Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Ivanov,A.,Am Diet Assoc 109 (2), 313-318 (2009) Schmidt A., Biochemistry 39:6325-6335(2000) Hol F.A., Clin. Genet. 53:119-125(1998)
NCBI	MTHFD1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C-1-tetrahydrofolate synthase, cytoplasmic, C1-THF synthase, Methylenetetrahydrofolate dehydrogenase, Methenyltetrahydrofolate cyclohydrolase, Formyltetrahydrofolate synthetase, C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed, MTHFD1, M
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	102 kDa
Manufacturer - Research Area	Cell Cycle, Obesity, Signal Transduction
Background	MTHFD1 is a protein that possesses three distinct enzymatic activities, 5, 10-methylenetetrahydrofolate dehydrogenase, 5, 10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
By Type	Cell Cycle, Obesity, Signal Transduction
Modifications	None
Protein Gi #	115206
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50 For IHC-P starting dilution is: 1:50~100
Homology	Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen	This MTHFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 535-562 amino acids from the Central region of human MTHFD1.
Clonality	Polyclonal
NCBI Official Name	C-1-tetrahydrofolate synthase, cytoplasmic
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names	C-1-tetrahydrofolate synthase, cytoplasmic, C1-THF synthase, Methylenetetrahydrofolate dehydrogenase, Methenyltetrahydrofolate cyclohydrolase, Formyltetrahydrofolate synthetase, C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed, MTHFD1, MTHFC, MTHFD

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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