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S6K Antibody

ArtNr PRS-61-629-200ul
Hersteller ProSci
Menge 200 ul
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Adem, C., et al., Genes Chromosomes Cancer 41(1):1-11 (2004).
Suzuki, Y., et al., Genome Res. 14(9):1711-1718 (2004).
Gomez-Cambronero, J., et al., Leuk. Res. 28(7):755-762 (2004).
Raught, B., et al., EMBO J. 23(8):1761-1769 (2004).
NCBI RPS6KB1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, 70 kDa ribosomal protein S6 kinase 1, P70S6K1, p70-S6K 1, Ribosomal protein S6 kinase I, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, RPS6KB1, STK14A
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
59 kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Obesity, Neuroscience, Signal Transduction
Background
RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
Protein Gi #
54041234
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Immunogen
This S6K (RPS6KB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 425-454 amino acids from human S6K (RPS6KB1).
Clonality
Polyclonal
NCBI Official Name
Ribosomal protein S6 kinase beta-1
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ul
Lieferbar: In stock
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