MMP25 Antibody

ArtNr	PRS-62-178-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Antibodies Western Blot Cardiovascular Research Atherosclerosis Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Matsuda, A., et al., J. Biol. Chem. 278(38):36350-36357 (2003). Velasco, G., et al., Cancer Res. 60(4):877-882 (2000). Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999). Pei, D., Cell Res. 9(4):291-303 (1999).
NCBI	MMP25
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Matrix metalloproteinase-25, MMP-25, 3424-, Leukolysin, Membrane-type matrix metalloproteinase 6, MT-MMP 6, MTMMP6, Membrane-type-6 matrix metalloproteinase, MT6-MMP, MT6MMP, MMP25, MMP20, MMPL1, MT6MMP
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Manufacturer - Applications	For WB starting dilution is: 1:1000
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	63 kDa
Manufacturer - Research Area	Cancer, Cell Cycle, Signal Transduction
Background	Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).
Protein Gi #	12585274
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen	This MMP25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP25.
Clonality	Polyclonal
NCBI Official Name	Matrix metalloproteinase-25
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 04.09.2025

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