Vergleich

M Sirt3 Antibody

ArtNr PRS-62-194-200ul
Hersteller ProSci
Menge 200 ul
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IHC-P
Specific against Mouse (Murine, Mus musculus), Hamster
Host Rabbit
Konjugat/Tag Unconjugated
Citations Hirschey, M.D., et al. Nature 464(7285):121-125(2010)
Pillai, V.B., et al. J. Biol. Chem. 285(5):3133-3144(2010)
Kim, H.S., et al. Cancer Cell 17(1):41-52(2010)
NCBI Sirt3
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NAD-dependent protein deacetylase sirtuin-3, 351-, Regulatory protein SIR2 homolog 3, SIR2-like protein 3, mSIR2L3, Sirt3, Sir2l3
Lieferbar
Manufacturer - Applications
For WB starting dilution is: 1:2000

For IHC-P starting dilution is: 1:50~100
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
blue ice or room temperature
Storage Conditions
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
37 kDa
Manufacturer - Research Area
Cancer, Cell Cycle, Obesity
Background
SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Immunogen
This Sirt3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-334 amino acids from the C-terminal region of Mouse Sirt3.
Clonality
Polyclonal
NCBI Official Name
NAD-dependent protein deacetylase sirtuin-3
NCBI Organism
Mus musculus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ul
Lieferbar: In stock
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