PTP epsilon Antibody

Primary Antibodies

Blue Ice

81 kDa

PTPepsilon is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of the gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

None

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Supplied in PBS with 0.09% (W/V) sodium azide.

This PTP epsilon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-589 amino acids from the C-terminal region of human PTP epsilon.

Receptor-type tyrosine-protein phosphatase epsilon

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.