CYP8B1 Antibody

ArtNr	PRS-63-644-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Neuroscience Neuroinflammation Metabolism Cholesterol & Lipid Metabolism Antibodies Cell Biology Cell Culture Cytokines Flow Cytometry Immunohistochemistry Western Blot Enzymes Prostaglandin Synthases Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Zhang,M. et.al., J. Biol. Chem. 276 (45), 41690-41699 (2001) Wang,J., et.al., Histochem. Cell Biol. 123 (4-5), 441-446 (2005)
NCBI	CYP8B1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase,7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase,CYPVIIIB1,Cytochrome P450 8B1,Sterol 12-alpha-hydroxylase,CYP8B1,CYP12
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	58 kDa
Manufacturer - Research Area	Obesity, Signal Transduction
Background	CYP8B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha, 12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless.
By Type	Obesity, Signal Transduction
Modifications	None
Protein Gi #	308153428
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50
Immunogen	This CYP8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-501 amino acids from the C-terminal region of human CYP8B1.
Clonality	Polyclonal
NCBI Official Name	7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 400 ul

lieferbar

Lieferung vsl. bis 01.01.2026

Express-Lieferung: 23 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern