TYROBP Antibody

ArtNr	PRS-64-155-400ul
Hersteller	ProSci
Menge	400 ul
Kategorie	Oncology Neuroscience Neural Lineage Markers Aging & Neurological Disorders Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Immunohistochemistry Western Blot Primary Antibodies Oligodendrocyte Markers
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, FC, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Konjugat/Tag	Unconjugated
Citations	Chen, X., et al. Blood 113(14):3226-3234(2009) Sulonen, A.M., et al. J. Neuroimmunol. 206 (1-2), 86-90 (2009) Lanier, L.L. Immunol. Rev. 227(1):150-160(2009) Schleinitz, N., et al. PLoS ONE(7), E6264 (2009)
NCBI	TYROBP
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TYRO protein tyrosine kinase-binding protein, DNAX-activation protein 12, Killer-activating receptor-associated protein, KAR-associated protein, TYROBP, DAP12, KARAP
Lieferbar
Manufacturer - Applications	For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 For FACS starting dilution is: 1:10~50
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	blue ice or room temperature
Storage Conditions	Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	12 kDa
Manufacturer - Research Area	Signal Transduction
Background	TYROBP encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL.
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	Batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Homology	Predicted species reactivity based on immunogen sequence: Bovine
Immunogen	This TYROBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human TYROBP.
Clonality	Polyclonal
NCBI Official Name	TYRO protein tyrosine kinase-binding protein
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 400 ul

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Lieferung vsl. bis 04.09.2025

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