PIERCE1 Antibody

Primary Antibodies

PIERCE1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

PIERCE1 Antibody: PIERCE1, also known as C9orf116, is an important p53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation. PIERCE1 exists as two alternatively spliced isoforms and is predominantly expressed in human small cell lung cancer. PIERCE1 knockdown induces down-regulation of proapoptotic genes including Ei24, Apaf1 and PTEN, suggesting that PIERCE1 is a proapoptotic gene. It is helpful for in-depth understanding of p53 pathways and the design of new cancer therapies.

Trial Size

115430217

PRS-1288-0.1mg

1 mg/mL

PIERCE1 antibody can be used for detection of PIERCE1 by Western blot at 1 μ g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ g/mL.
Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested.

PIERCE1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human PIERCE1.

The immunogen is located within the first 50 amino acids of PIERCE1.

chromosome 9 open reading frame 116

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.