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CD20 Antibody [AISB12]

ArtNr PRS-76-010-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC, FA
Clon AISB12
Specific against Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG2a
Konjugat/Tag Unconjugated
Citations Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., Tedder, T. F. (2004). The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptordependent mechanisms during anti-CD20 antibody immunotherapy.The Journal of experimental medicine,199(12), 1659-1669.
Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... Tedder, T. F. (2004). Mouse CD20 expression and function.International immunology,16(1), 119-129.
Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... Yi, Q. (2012). Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma.Blood,119(1), 161-169.
NCBI Ms4a1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Cd20,Ly-44,Ms4a2,AA960661,Ms4a1
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies, Functional Antibodies
Manufacturer - Isotype
Rat IgG2a
Shipping Temperature
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Manufacturer - Research Area
Immunology, Functional Assays
Background
The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.
By Type
Immunology
Modifications
None
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Manufacturer - Specificity
The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule.
Clonality
Monoclonal
NCBI Official Name
membrane-spanning 4-domains, subfamily A, member 1
NCBI Organism
Mus musculus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
lieferbar

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