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CD62L Antibody [DREG-56]

CD62L Antibody [DREG-56]

ArtNr	PRS-76-212-0.5mg
Hersteller	ProSci
Menge	0.5 mg
Kategorie	Neuroscience Neuroinflammation Neural Signaling Neural Adhesion Molecules Antibodies Cell Biology Cell Movement Cell Adhesion Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	FC, FA
Clon	DREG-56
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	Unconjugated
Citations	Schlossman, S. F. (1995).Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Kishimoto, T. K., Jutila, M. A., Butcher, E. C. (1990). Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.Proceedings of the National Academy of Sciences,87(6), 2244-2248. Kishimoto, T. K., Warnock, R. A., Jutila, M. A., Butcher, E. C., Lane, C., Anderson, D. C., Smith, C. W. (1991). Antibodies against human neutrophil LECAM-1 (LAM-1/Leu-8/DREG-56 antigen) and endothelial cell ELAM-1 inhibit a common CD18-independent adhesion pathway in vitro.Blood,78(3), 805-811.
NCBI	SELL
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TQ1,LAM1,LEU8,LNHR,LSEL,CD62L,LYAM1,PLNHR,LECAM1,SELL
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies, Functional Antibodies
Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C . Do not freeze.
Manufacturer - Research Area	Immunology, Functional Assays
Background	The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1. It mediates the migration of lymphocytes to the site of inflammation and their return to the peripheral lymphoid tissues and to the HEV (high endothelial venules). CD62L is expressed on monocytes, NK cells, neutrophils, granulocytes, and subsets of T and B cells. It is reported that the DREG-56 antibody inhibits the binding of lymphocytes to HEV tissue in frozen peripheral tissue.
By Type	Immunology
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Manufacturer - Specificity	The DREG-56 monoclonal antibody specifically reacts with human CD62L, also known as L-selectin and LECAM-1.
Clonality	Monoclonal
NCBI Official Name	selectin L
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.5 mg

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Lieferung vsl. bis 04.12.2025

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