CD3 Antibody [17A2]

ArtNr	PRS-76-224-0.5mg
Hersteller	ProSci
Menge	0.5 mg
Kategorie	Antibodies Flow Cytometry Immunohistochemistry Immunoprecipitation Primary Antibodies
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC, IP, IHC
Clon	17A2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b Kappa
Konjugat/Tag	Unconjugated
Citations	Miescher, G. C., Schreyer, M., MacDonald, H. R. (1989). Production and characterization of a rat monoclonal antibody against the murine CD3 molecular complex.Immunology letters,23(2), 113-118. Mysliwietz, J., Thierfelder, S. (1992). Antilymphocytic antibodies and marrow transplantation. XII. Suppression of graft-versus-host disease by T-cell-modulating and depleting antimouse CD3 antibody is most effective when preinjected in the marrow recipient.Blood,80(10), 2661-2667. Wu, L., Antica, M., Johnson, G. R., Scollay, R., Shortman, K. (1991). Developmental potential of the earliest precursor cells from the adult mouse thymus.The Journal of experimental medicine,174(6), 1617-1627.
NCBI	Cd3e
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD3, T3e, AI504783, CD3epsilon, Cd3e
Lieferbar
Manufacturer - Isotype	Rat IgG2b, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C . Do not freeze.
Manufacturer - Research Area	Immunology, Functional Assays
Background	The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains gamma, delta, and epsilon subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 epsilon chain.
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Clonality	Monoclonal
NCBI Official Name	CD3 antigen, epsilon polypeptide
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 0.5 mg

lieferbar

Lieferung vsl. bis 02.10.2025

Express-Lieferung: 22 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern