CD19 Antibody [1D3] (PE-Cy7)

Rat IgG2a, kappa

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

The 1D3 monoclonal antibody specifically reacts with MouseCD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.

None

batch dependent

The 1D3 monoclonal antibody specifically reacts with MouseCD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells.

CD19 antigen

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.