« Zurück
Startseite /
CD49b Antibody [HMa2]

CD49b Antibody [HMa2]

ArtNr	PRS-76-808-0.5mg
Hersteller	ProSci
Menge	0.5 mg
Kategorie	Neuroscience Aging & Neurological Disorders Neural Adhesion Molecules Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	FC, FA
Clon	HMa2
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Baron, J. L., Reich, E. P., Visintin, I., Janeway Jr, C. A. (1994). The pathogenesis of adoptive murine autoimmune diabetes requires an interaction between alpha 4-integrins and vascular cell adhesion molecule-1.Journal of Clinical Investigation,93(4), 1700. Chisholm, P. L., Williams, C. A., Lobb, R. R. (1993). Monoclonal antibodies to the integrin alpha 4 subunit inhibit the murine contact hypersensitivity response.European journal of immunology,23(3), 682-688. Holzmann, B., McIntyre, B. W., Weissman, I. L. (1989). Identification of a murine Peyer's patchspecific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4alpha .Cell,56(1), 37-46.
NCBI	Itga2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	DX5,CD49B,Itga2
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies, Functional Antibodies
Manufacturer - Isotype	Armenian Hamster IgG
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C . Do not freeze.
Manufacturer - Research Area	Immunology, Functional Assays
Background	The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1). VLA-2 is expressed on NK-T cells, epithelial cells, platelets, and CD+4 T lymphocytes. It is the receptor for laminin and collagen and is upregulated in response to mitogens. The Hma2 antibody is reported to partially block the interaction with collagen in T cells, but not NK cells.
By Type	Immunology
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ph7.2.
Manufacturer - Specificity	The HMa2 monoclonal antibody specifically reacts with mouse CD49b (integrin alpha 2), a 150kDA transmembrane glycoprotein that forms the VLA-2 complex with CD29 (integrin beta 1).
Clonality	Monoclonal
NCBI Official Name	integrin alpha 2
NCBI Organism	Mus musculus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 0.5 mg

lieferbar

Lieferung vsl. bis 06.11.2025

Express-Lieferung: 1 Tage sparen

Vergleichen

Auf den Wunschzettel

Angebot anfordern