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CD154 Antibody [MR1] (PE)

ArtNr PRS-76-870-0.025mg
Hersteller ProSci
Menge 0.025 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen FC
Clon MR1
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Armenian
Isotype IgG
Konjugat/Tag PE
Citations Frster, R., Kremmer, E., Schubel, A., Breitfeld, D., Kleinschmidt, A., Nerl, C., ... Lipp, M. (1998). Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation.The Journal of Immunology,160(3), 1522-1531.
Schabath, R., M, G., Schubel, A., Kremmer, E., Lipp, M., Frster, R. (1999). The murine chemokine receptor CXCR4 is tightly regulated during T cell development and activation.Journal of leukocyte biology,66(6), 996-1004.
Gupta, S. K., Lysko, P. G., Pillarisetti, K., Ohlstein, E., Stadel, J. M. (1998). Chemokine Receptors in Human Endothelial Cells FUNCTIONAL EXPRESSION OF CXCR4 AND ITS TRANSCRIPTIONAL REGULATION BY INFLAMMATORY CYTOKINES.Journal of Biological Chemistry,273(7), 4282-4287.
NCBI Cd40lg
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias IGM,IMD3,Ly62,TRAP,gp39,CD154,Cd40l,HIGM1,Ly-62,T-BAM,CD40-L,Tnfsf5,Cd40lg
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Armenian Hamster IgG
Shipping Temperature
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Immunology
Background
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.
By Type
Immunology
Modifications
None
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity
The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39.
Clonality
Monoclonal
NCBI Official Name
CD40 ligand
NCBI Organism
Mus musculus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.025 mg
Lieferbar: In stock
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