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CD106 Antibody [STA] (PE)

ArtNr PRS-76-884-25tests
Hersteller ProSci
Menge 25 tests
Kategorie
Typ Antibody Monoclonal
Format liquid
Applikationen FC
Clon STA
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag PE
Citations Elshal, M. F., Khan, S. S., Takahashi, Y., Solomon, M. A., McCoy, J. P. (2005). CD146 (Mel-CAM), an adhesion marker of endothelial cells, is a novel marker of lymphocyte subset activation in normal peripheral blood.Blood,106(8), 2923-2924.
Shih, I. M. (1999). The role of CD146 (Mel‐CAM) in biology and pathology.The Journal of pathology,189(1), 4-11.
Solovey, A. N., Gui, L., Chang, L., Enenstein, J., Browne, P. V., Hebbel, R. P. (2001). Identification and functional assessment of endothelial P1H12.Journal of Laboratory and Clinical Medicine,138(5), 322-331.
NCBI ENG
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias END, HHT1, ORW1, ENG
Lieferbar
Manufacturer - Isotype
Mouse IgG1, kappa
Shipping Temperature
blue ice or room temperature
Storage Conditions
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Immunology
Background
The STA monoclonal antibody specifically reacts with human CD106, a 110 kDA glycoprotein also named Vascular Cell Adhesion Molecule-1 (VCAM-1) and INCAM-110. Its expression is induced by inflammation stimuli and cytokines and it is found mainly on activated vascular endothelium. CD106 is also found on subsets of macrophages, stromal cells, dendritic cells, and myeloid lineage cells. The integrins that bind CD106 are CD49d/CD29 and LPAM-1, and it is involved in cell adhesion, transmigration and T cell proliferation.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality
Monoclonal
NCBI Official Name
endoglin
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 tests
Lieferbar: In stock
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