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CD107a Antibody [H4A3] (PE)

ArtNr PRS-76-892-25tests
Hersteller ProSci
Menge 25 tests
Kategorie
Typ Antibody Monoclonal
Format liquid
Applikationen FC
Clon H4A3
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag PE
Citations Chen, J. W., Cha, Y. I. N. G., Yuksel, K. U., Gracy, R. W., August, J. T. (1988). Isolation and sequencing of a cDNA clone encoding lysosomal membrane glycoprotein mouse LAMP-1. Sequence similarity to proteins bearing onco-differentiation antigens.Journal of Biological Chemistry,263(18), 8754-8758.
Grtzkau, A., Smorodchenko, A., Lippert, U., Kirchhof, L., Artuc, M., Henz, B. M. (2004). LAMP‐1 and LAMP‐2, but not LAMP‐3, are reliable markers for activation‐induced secretion of human mast cells.Cytometry Part A,61(1), 62-68.
Sarafian, V., Jadot, M., Foidart, J. M., Letesson, J. J., Van den Brule, F., Castronovo, V., ... Coninck, W. D. (1998). Expression of Lamp‐1 and Lamp‐2 and their interactions with galectin‐3 in human tumor cells.International journal of cancer,75(1), 105-111.
NCBI LAMP1
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias LAMPA, CD107a, LGP120, LAMP1
Lieferbar
Manufacturer - Isotype
Mouse IgG1, kappa
Shipping Temperature
blue ice or room temperature
Storage Conditions
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Innate Immunity
Background
The H4A3 monoclonal antibody specifically reacts with human CD107a, a heavily glycosylated type I membrane glycoprotein. CD107a is also known as Lysosomal-associated membrane protein 1 (LAMP-1) and is widely expressed intracellular antigen. It can be found on the surface of PHA-activated lymphocytes, activated platelets, cytotoxic T cells, NK cells, macrophages, epithelial cells, endothelial cells, and some tumor lines. CD107a is a ligand for E-selectin and galaptin and is reported to be involved in cell adhesion and tumor metastasis.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality
Monoclonal
NCBI Official Name
lysosomal-associated membrane protein 1
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 tests
Lieferbar: In stock
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