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CD117 Antibody [ACK2]

ArtNr PRS-76-896-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IHC, ICC, FA
Clon ACK2
Specific against Mouse (Murine, Mus musculus)
Host Rat
Isotype IgG2b Kappa
Konjugat/Tag Unconjugated
Citations Godfrey, D. I., Kennedy, J., Mombaerts, P., Tonegawa, S., Zlotnik, A. (1994). Onset of TCR-beta gene rearrangement and role of TCR-beta expression during CD3-CD4-CD8-thymocyte differentiation. The Journal of Immunology,152(10), 4783-4792.
Godfrey, D. I., Zlotnik, A. L. B. E. R. T., Suda, T. A. K. A. S. H. I. (1992). Phenotypic and functional characterization of c-kit expression during intrathymic T cell development.The Journal of Immunology,149(7), 2281-2285.
Feng, H., Sandlow, J. I., Sandra, A. (1998). The c-kit receptor and its possible signaling transduction pathway in mouse spermatozoa.Molecular reproduction and development,49(3), 317-326.
NCBI Kit
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias W,Bs,Fdc,Ssm,SCO1,SCO5,SOW3,CD117,c-KIT,Tr-kit,Gsfsco1,Gsfsco5,Gsfsow3,Kit
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies, Functional Antibodies
Manufacturer - Isotype
Rat IgG2b, kappa
Shipping Temperature
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Manufacturer - Research Area
Functional Assays
Background
The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene. The c-Kit receptor, also known as stem cell factor receptor, is expressed on hematopoietic progenitor cells in adult bone marrow, in progenitors of erythroid and myeloid lineages, and precursors of B and T cells. CD117 enhances the proliferation and the differentiation of the hematopoietic progenitor cells and seems to enhance the development of T cells, as the c-Kit receptor and its ligand are expressed by the thymus.
By Type
Other
Modifications
None
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Manufacturer - Specificity
The ACK2 monoclonal antibody specifically reacts with mouse CD117 (c-Kit receptor), a 145 kDa transmembrane tyrosine-kinase receptor encoded by the Kit gene.
Clonality
Monoclonal
NCBI Official Name
kit oncogene
NCBI Organism
Mus musculus
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
lieferbar

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