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CD117 Antibody [YB5.B8] (PE)

CD117 Antibody [YB5.B8] (PE)

ArtNr	PRS-76-905-25tests
Hersteller	ProSci
Menge	25 tests
Kategorie	Oncology Antibodies Flow Cytometry Primary Antibodies By Organ Colorectal Cancer Heart & Blood Cancer
Typ	Antibody Monoclonal
Format	liquid
Applikationen	FC
Clon	YB5.B8
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	PE
Citations	Sudo, T., Nishikawa, S. A. T. O. M. I., Ohno, N. O. R. I. K. O., Akiyama, N. A. O. K. O., Tamakoshi, M. A. S. A. T. A. D. A., Yoshida, H. I. S. A. H. I. R. O. (1993). Expression and function of the interleukin 7 receptor in murine lymphocytes.Proceedings of the National Academy of Sciences,90(19), 9125-9129. Hashi, H., Yoshida, H., Honda, K., Fraser, S., Kubo, H., Awane, M., ... Nishikawa, S. I. (2001). Compartmentalization of Peyers patch anlagen before lymphocyte entry.The Journal of Immunology,166(6), 3702-3709. Okuno, Y., Iwasaki, H., Huettner, C. S., Radomska, H. S., Gonzalez, D. A., Tenen, D. G., Akashi, K. (2002). Differential regulation of the human and murine CD34 genes in hematopoietic stem cells.Proceedings of the National Academy of Sciences,99(9), 6246-6251.
NCBI	KIT
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	PBT, SCFR, C-Kit, CD117, KIT
Lieferbar
Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	blue ice or room temperature
Storage Conditions	The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Stem Cell
Background	The YB5.B8 monoclonal antibody specifically binds with human CD117 (c-kit), the 145 kDA receptor for stem cell factor (SCF) or steel factor. This tyrosine kinase protein is expressed mainly on hematopoietic progenitor, mast cells, acute myeloid leukemia cells (AML). CD117 activation promotes proliferation and cell differentiation on these cell subtypes. A lack or defect of SCF can lead to a decrease in number of hematopoietic progenitor cells and severe anemia.
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	Batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality	Monoclonal
NCBI Official Name	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 25 tests

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Lieferung vsl. bis 02.10.2025

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