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CD127 Antibody [RDR5] (PE-Cy5)

CD127 Antibody [RDR5] (PE-Cy5)

ArtNr	PRS-76-927-100tests
Hersteller	ProSci
Menge	100 tests
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Primary Antibodies By Organ Lung Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	FC
Clon	RDR5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	PE, Cy5
Citations	Sallusto, F., Lenig, D., Frster, R., Lipp, M., Lanzavecchia, A. (1999). Two subsets of memory T lymphocytes with distinct homing potentials and effector functions.Nature,401(6754), 708-712. Yoshida, R., Nagira, M., Imai, T., Baba, M., Takagi, S., Tabira, Y., ... Yoshie, O. (1998). EBI1-ligand chemokine (ELC) attracts a broad spectrum of lymphocytes: activated T cells strongly up-regulate CCR7 and efficiently migrate toward ELC.International immunology,10(7), 901-910. Lee, N., Llano, M., Carretero, M., Ishitani, A., Navarro, F., Lpez-Botet, M., Geraghty, D. E. (1998). HLA-E is a major ligand for the natural killer inhibitory receptor CD94/NKG2A.Proceedings of the National Academy of Sciences,95(9), 5199-5204.
NCBI	IL7R
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ILRA,CD127,IL7RA,CDW127,IL-7R-alpha,IL7R
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Mouse IgG1, kappa
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Chemokines & Cytokines, Growth Factors
Background	The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain. CD127 binds with CD132 (gamma c) to forms the IL-7 receptor that is expressed on mature T cells and immature B cells. Since CD127 expression is downregulated in Treg cells, it can be used as a marker for differentiating them from common T cells. The binding of the RDR5 antibody can be blocked by pre-incubating the cells with human IL-7.
By Type	Chemokines & Cytokines, Growth Factors
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity	The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain.
Clonality	Monoclonal
NCBI Official Name	interleukin 7 receptor
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 tests

lieferbar

Lieferung vsl. bis 06.11.2025