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CD243 Antibody [UIC2] (PE)

CD243 Antibody [UIC2] (PE)

ArtNr	PRS-76-952-100tests
Hersteller	ProSci
Menge	100 tests
Kategorie	Oncology Antibodies By Cell Type Carcinoma Hematology Leukemia Sarcoma Flow Cytometry Primary Antibodies By Organ Breast Cancer Pancreatic Cancer
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	FC
Clon	UIC2
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	PE
Citations	Tseng, S. Y., Otsuji, M., Gorski, K., Huang, X., Slansky, J. E., Pai, S. I., ... Tsuchiya, H. (2001). B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells.The Journal of experimental medicine,193(7), 839-846. Wang, S., Bajorath, J., Flies, D. B., Dong, H., Honjo, T., Chen, L. (2003). Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction.The Journal of experimental medicine,197(9), 1083-1091. Aramaki, O., Shirasugi, N., Takayama, T., Shimazu, M., Kitajima, M., Ikeda, Y., ... Niimi, M. (2004). Programmed death-1-programmed death-L1 interaction is essential for induction of regulatory cells by intratracheal delivery of alloantigen.Transplantation,77(1), 6-12.
NCBI	ABCB1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CLCS,MDR1,P-GP,PGY1,ABC20,CD243,GP170,ABCB1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Mouse IgG2a
Shipping Temperature	Blue Ice
Storage Conditions	The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area	Stem Cell
Background	The UIC2 monoclonal antibody specifically reacts with CD243, a 170 kDA transmembrane protein also known as human multidrug resistant-1 (MDR-1) or P-glycoprotein (Pgp). It is an ATP binding cassette (ABC) transport and is expressed on B, T, NK cells to the exclusion of monocytes. CD243 is involved in the process that transports molecules across the cellular membranes and plays a role in multidrug resistance. The UIC2 antibody inhibits CD243 mediated efflux.
By Type	Stem Cell
Modifications	None
Purification	The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration	batch dependent
Buffer	Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Manufacturer - Specificity	The UIC2 monoclonal antibody specifically reacts with CD243, a 170 kDA transmembrane protein also known as human multidrug resistant-1 (MDR-1) or P-glycoprotein (Pgp).
Clonality	Monoclonal
NCBI Official Name	ATP-binding cassette, sub-family B (MDR/TAP), member 1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 tests

lieferbar

Lieferung vsl. bis 06.11.2025