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CD289 Antibody [72-1665] (PE)

ArtNr PRS-76-972-0.025mg
Hersteller ProSci
Menge 0.025 mg
Kategorie
Typ Antibody Monoclonal
Format liquid
Applikationen FC
Clon 72-1665
Specific against Human (Homo sapiens)
Host Rat
Isotype IgG2a Kappa
Konjugat/Tag PE
Citations Zhang, J. Y., Zhang, Z., Wang, X., Fu, J. L., Yao, J., Jiao, Y., ... Wang, F. S. (2007). PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors.Blood,109(11), 4671-4678.
Bennett, F., Luxenberg, D., Ling, V., Wang, I. M., Marquette, K., Lowe, D., ... Carreno, B. M. (2003). Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses.The Journal of Immunology,170(2), 711-718.
Thompson, R. H., Dong, H., Lohse, C. M., Leibovich, B. C., Blute, M. L., Cheville, J. C., Kwon, E. D. (2007). PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma.Clinical Cancer Research,13(6), 1757-1761.
NCBI TLR9
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias TLR9, TLR9
Lieferbar
Manufacturer - Isotype
Rat IgG2a, kappa
Shipping Temperature
blue ice or room temperature
Storage Conditions
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Manufacturer - Research Area
Innate Immunity
Background
The 72-1665 monoclonal antibody specifically reacts with CD289, also known as human toll-like receptor 9 (TLR9). CD289 is involved in the activation of innate immunity, in acquired immune responses, and autoimmune diseases. It is involved in the immune system’s response to unmethylated CpG dinucleotide sequences such as those found in bacterial, viral, or synthetic DNA. CD289 assists in pathogen recognition and is expressed by subtypes of dendritic cells and B cells.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Clonality
Monoclonal
NCBI Official Name
toll-like receptor 9
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.025 mg
Lieferbar: In stock
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